The cannabinoids work on the endocannabinoid system in our body, helping the body maintain balance and supporting the immune system. The various cannabinoids have medicinal properties for the treatment of pain, nausea, depression, neurological problems, immune system diseases, skin problems, diabetes, cancer and more …
In the fresh plant, cannabinoids are acidic. After heating, a group of carboxylic (decarboxylation) is released. Every cannabinoid breaks down at a certain temperature. An aging and aging plant – decomposes more cannabinoids and has a different effect than fresh ones – may also put the user to sleep.
What is special about cannabinoids over other plant pharmacological substances is that, like opium, they are absorbed in our body by receptors designed to absorb substances similar to them, substances produced in our body called endocannabinoids.
In our body, an endocannabinoid system knows how to absorb the cannabinoids in cannabis because its cofactor produces similar substances. In the picture: the activity of cannabinoids in the synapse – the space between a nerve cell and a target cell (which may also be another nerve cell)
THC Trachidrocannabinol – the main psychoactive component of the cannabis plant. Was first isolated in 1964, in its pure form, by Israeli chemists Raphael Meshulam and Yehiel Geni at the Weizmann Institute of Science. When it is cold it is solid and glazed, and when heated becomes sticky and viscous. THC is synthetically called: dronabinol. You can buy a prescription in the United States and Canada under the Marinol brand name. Because it is classified as aromatic trapeanoid to THC, it has a very low ability to dissolve in water and good ability to dissolve in organic solvents especially oils and alcohol.
CBD Cannabidiol has a wider range of medical applications than THC. Suitable for treating epilepsy, autism, anxiety, schizophrenia, Alzheimer’s, migraines, relief nausea and vomiting, anti-inflammatory, arthritis, psoriasis and more …
Oral oral fluid containing CBD has been granted the status of an orphan drug in the United States for use in the treatment of a type of epilepsy-induced dervous syndrome under the brand name Epidiolex.
CBG Cannabigerol is a non-psychoactive cannabinoid produced in the young cannabis plant during the early stages of the growth cycle. Originally it appears in its acid form, CBGA, and after heating, it becomes CBG, similar to the processes undergone by the THCA and CBDA. CBG is actually the source of all other cannabinoids. When the plant reaches the flowering stage, it releases enzymes that convert CBG to other cannabinoids such as THC and CBD. For this reason, the concentration of CBG in the final produced from most varieties is low.
CBN-Cannabinol is a decomposition product of THC and can be used to test how fresh the inflorescence is.
There are many more cannabinoids and there is not enough research about them.